{"id":83,"date":"2017-01-10T12:09:45","date_gmt":"2017-01-10T11:09:45","guid":{"rendered":"http:\/\/www.mojidoktori.rs\/blog\/?p=83"},"modified":"2017-01-12T12:17:18","modified_gmt":"2017-01-12T11:17:18","slug":"osteoporoza","status":"publish","type":"post","link":"https:\/\/www.mojidoktori.rs\/blog\/osteoporoza\/","title":{"rendered":"Osteoporoza"},"content":{"rendered":"
Osteoporoza (poroznost kostiju)<\/strong><\/span><\/h5>\n
\n

Osteoporoza je bolest koja se manifestuje smanjenjem gustine kostiju, zbog \u010dega one postaju porozne. Smanjuje se koli\u010dina kalcijuma koji normalno osigurava \u010dvrstinu kosti i ko\u0161tanog tkiva, koje omogu\u0107ava potpornu funkciju kostima. Takve krhke i porozne kosti poja\u010dano su osetljive na razli\u010dite fizi\u010dke stresove (udarce, padove). Osteoporoza je jedan od glavnih uzroka ozbiljnog invaliditeta starijih ljudi. Prelom kuka uzrokovan osteoporozom zahvata jednu od tri \u017eene i jednog od pet mu\u0161karaca u dobi do osamdeset i pet godina.\u00a0 Uprkos postojanju objektivnih mogu\u0107nosti, osteoporoza je i dalje nedovoljno dijagnostikovana i le\u010dena.<\/span><\/p>\n

Epidemiolo\u0161ki status<\/span><\/h5>\n
Osteoporoza je bolest sa kojom se suo\u010dava populacija tzv. „tre\u0107eg \u017eivotnog doba“, odnosno starije osobe. Od osteoporoze boluje 75 miliona ljudi u Evropi, SAD-u i Japanu. Smatra se da je u Srbiji ovom bole\u0161\u0107u pogo\u0111eno oko 375 hiljada \u017eena. Prema najnovijim istra\u017eivanjima broj ljudi kod kojih je ustanovljena osteoporoza \u0107e se udvostru\u010diti u narednih 50 godina, usled starenja svetske populacije i uticaja raznih faktora, me\u0111u kojima zna\u010dajno mesto zauzima na\u010din \u017eivota.<\/span><\/div>\n
\u00a0Klini\u010dka slika<\/span><\/h5>\n
Problem kod ove bolesti je to \u0161to proti\u010de naj\u010de\u0161\u0107ebez simptoma, do trenutka kada nastaju najte\u017ee posledice, odnosno frakture. Smanjenje visine, pogrbljenost i bolovi u le\u0111ima naj\u010de\u0161\u0107e se pripisuju drugim razlozima ili jednostavno starenju. Smanjenje ko\u0161tane gustine je pra\u0107eno i uve\u0107anim rizikom za nastanak preloma, \u010desto nakon minimalnih trauma. Njen neizbe\u017ean pratilac je visoka u\u010destalost preloma pr\u0161ljenskih tela i vrata butne kosti sa velikim patnjama i invalidno\u0161\u0107u.<\/span><\/div>\n
\n

Postoje dva razli\u010dita tipa osteoporoze :<\/span><\/p>\n

 <\/p>\n<\/div>\n

    \n
  • tip 1 ili postmenopauzalna osteoporoza i<\/span><\/li>\n
  • tip 2 ili senilna (stara\u010dka) osteoporoza.<\/span><\/li>\n<\/ul>\n
    \n

    Postmenopauzalna osteoporoza se javlja kod \u017eena nakon menopauze (poslednje menstruacije), pra\u0107ena je prelomima pr\u0161ljenova.<\/span><\/p>\n

    Senilna osteoporoza se javlja u oba pola nakon 70. godine, prezentuje se poglavito prelomima kuka i uzrokovana je starenjem.<\/span><\/p>\n

    Naj\u010de\u0161\u0107i uzroci sekundarne osteoporoze (uzrokovane bolestima ili lekovima) su : le\u010denje steroidima i antikonvulzivima (lekovi za le\u010denje epilepsije). Osteoporoza dugo vremena ostaje klini\u010dki neupadljiva \u2013 ona nema karakteristi\u010dne simptome i \u0161to je najva\u017enije, ne boli. Stoga se s pravom naziva „tihim kradljivcem“ jer godinama osiroma\u0161uje ko\u0161tanu masu sve dok ne spadne ispod takozvanog „praga za frakture“ kada se javljaju klini\u010dki dramati\u010dne komplikacije bolesti – prelomi pr\u0161ljenova.<\/span><\/p>\n

    Prelom pr\u0161ljenova naj\u010de\u0161\u0107e nastaje pri naglom pokretu, savijanju, dizanju tereta, a ponekada i bez ikakvog vidljivog povoda. Prelom pr\u0161ljena dovodi do pogurenog dr\u017eanja karakteristi\u010dnog za osteoporozu. Telesna visina se smanjuje sa svakim prelomom – oko 2-4 cm.<\/span><\/p>\n<\/div>\n

    \u00a0Le\u010denje<\/span><\/h5>\n
    \n

    Najsavremenije metode le\u010denja osteoporoze uklju\u010duju primenu novih lekova – bisfosfonata. Oni dokazano smanjuju rizik za nastanak vertebralnih i preloma kuka. To su sada najefektniji lekovi za le\u010denje osteoporoze i kod \u017eena i kod mu\u0161karaca.<\/span><\/p>\n

    Jedan od preparata koji je pokazao najbolje rezultate u primeni je Bonviva (ibandronat 150mg).\u00a0 Ovaj preparat spada u nehormonske lekove koji se koriste uprevenciji i le\u010denju osteoporoze i jedinstven je me\u0111u bisfosfonatima po tome \u0161to se uzima jednanput mese\u010dno, oralno. Bezbednost, efikasnost i tolerancija u odnosu na lek Bonviva prou\u010davani su kroz opse\u017ean program klini\u010dkih ispitivanja na oko 11.000 pacijenata u periodu od tri godine. U velikim registracionim studijama, ovaj lek pokazao je sna\u017eno antifrakturno dejstvo, tj. pospe\u0161uje gustinu\/\u010dvrstinu kostiju. Istra\u017eivanja pokazuju da \u0107e mogu\u0107nost re\u0111eg uzimanja leka pove\u0107ati izglede da se nastavi sa le\u010denjem.<\/span><\/p>\n<\/div>\n

    \u00a0Prevencija<\/span><\/h5>\n
    \n

    Najbitniji put u spre\u010davanju nastanka osteoporoze je prevencija. Dovoljan unos kalcijuma i vitamina D hranom vrlo su zna\u010dajan faktor u pravovremenoj za\u0161titi. Neophodno je da posmenopauzalne \u017eene unose 1200 mg kalcijuma i 400-800 IU vitamina D dnevno, da ve\u017ebaju ja\u010danje muskulature i\u00a0 izbegavaju preteranu upotrebu duvana, unosa alkohola i kafe. Dobri izvori kalcijuma u hrani\u00a0 su mleko polumasni jogurt, sir, brokoli, sok od narand\u017ee i drugi proizvodi.<\/span><\/p>\n

    Ve\u017ebanje mo\u017ee pomo\u0107i u izgradnji jakih kostiju i usporavanju gubitka ko\u0161tanog tkiva. Pu\u0161enje pove\u0107ava gubitak ko\u0161tanog tkiva, zbog smanjenja koli\u010dine estrogena koje telo proizvodi i smanjene apsorpcije kalcijuma iz creva. Supstituciona hormonska terapija je najva\u017enije sredstvo za smanjenje rizika od osteoporoze tokom i nakon menopauze. Vi\u0161e od dva alkoholna pi\u0107a dnevno mogu smanjiti formiranje kostiju i smanjiti telesnu sposobnost apsorpcije kalcijuma.<\/span><\/p>\n<\/div>\n

    \n

    Faktori rizika<\/span><\/h4>\n
      \n
    • \u017dene u menopauzi, posebno ako je nastupila rano<\/span><\/li>\n
    • Porodi\u010dna anamneza pojave osteoporoze (majka koja je imala prelom kuka usled osteoporoze duplo pove\u0107ava \u0161ansu potomstvu da ih zadesi isti problem)<\/span><\/li>\n
    • Pu\u0161enje<\/span><\/li>\n
    • Redovna upotreba alkohola<\/span><\/li>\n
    • Fizi\u010dka neaktivnost<\/span><\/li>\n
    • Slabo zdravstveno stanje i slab imunitet<\/span><\/li>\n
    • Hemoterapija koja mo\u017ee da dovede do prerane menopauze.<\/span><\/li>\n
    • Hipertireoidizam<\/span><\/li>\n
    • Hiperparatiroidizam<\/span><\/li>\n
    • Nedostatak vitamina D i kalcijuma u ishrani, a kasnije i hrane koja \u010duva dejstvo estrogena (soja) i testosterona (semenke bundeve)<\/span><\/li>\n
    • Hroni\u010dna zapaljenska stanja, kao \u0161to je hroni\u010dni glomerulonefritis<\/span><\/li>\n
    • Nepokretnost – posle neke traume, preloma ili \u0161loga.<\/span><\/li>\n
    • Upotreba nekih lekova (kortikosteroidi)<\/span><\/li>\n<\/ul>\n

      Kako se izboriti sa problemom<\/span><\/h4>\n
      Poseban vid ishrane vezan za osteoprozu svodi se uglavnom na pove\u0107ani unos<\/strong> hrane bogate kalcijumom, vitaminom D<\/strong>, hranom koja \u010duva dejstvo estrogena (soja) i testosterona (semenke bundeve), i kontrolu energetskog unosa jer pove\u0107ana telesna masa dodatno optere\u0107uje kosti<\/span><\/div>\n<\/div>\n<\/div>\n

       <\/p>\n","protected":false},"excerpt":{"rendered":"

      Osteoporoza (poroznost kostiju) Osteoporoza je bolest koja se manifestuje smanjenjem gustine kostiju, zbog \u010dega one postaju porozne. Smanjuje se koli\u010dina kalcijuma koji normalno osigurava \u010dvrstinu kosti i ko\u0161tanog tkiva, koje omogu\u0107ava potpornu funkciju kostima. Takve krhke i porozne kosti poja\u010dano su osetljive na razli\u010dite fizi\u010dke stresove (udarce, padove). Osteoporoza je…<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[103,107,108,106,101,102,104,109,105],"class_list":["post-83","post","type-post","status-publish","format-standard","hentry","category-blog","tag-epidemioloski-status","tag-hipertireoidizam","tag-kortikosteroidi","tag-lecenje-osteoporoze","tag-osteoporoza","tag-poroznost-kostiju","tag-postmenopauzalna-osteoporoza","tag-semenke-bundeve","tag-senilna-osteoporoza"],"yoast_head":"\nOsteoporoza - Popusti i kuponi<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.mojidoktori.rs\/blog\/osteoporoza\/\" \/>\n<meta property=\"og:locale\" content=\"sr_RS\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Osteoporoza - Popusti i kuponi\" \/>\n<meta property=\"og:description\" content=\"Osteoporoza (poroznost kostiju) Osteoporoza je bolest koja se manifestuje smanjenjem gustine kostiju, zbog \u010dega one postaju porozne. Smanjuje se koli\u010dina kalcijuma koji normalno osigurava \u010dvrstinu kosti i ko\u0161tanog tkiva, koje omogu\u0107ava potpornu funkciju kostima. Takve krhke i porozne kosti poja\u010dano su osetljive na razli\u010dite fizi\u010dke stresove (udarce, padove). 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